Strain Information | |
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Image | |
BRC No. | RBRC00142 |
Type | Spontaneous Mutation Congenic |
Species | Mus musculus |
Strain name | B6.Cg-Kit<W-v>/Rbrc |
Former Common name | C57BL/6-Kit<W-v>/+ |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | black [a/a B/B C/C +/+] white with black eyes [a/a B/B C/C W/W] gray with light belly, white spot, light tail an feet [a/a B/B C/C W/+] |
Strain development | Spontaneous mutation arosed in C57BL. |
Strain description | B6.Cg-Kit<W-v>. Viable dominant spotting. Spontaneous mutation arosed in C57BL. The Kit<W-v> mutation arose spontaneously in the C57BL strain. Heterozygote for Kit<W-v> are gray with light belly, white spot, light tail and feet. Homozygous mice are white with black eyes. The c-Kit cDNA from Kit<W-v>/Kit<W-v> mice showed an AC to T point mutation at nucleotide 2007 that resulted in the change from threonine to methionine at position 660. |
Colony maintenance | Sibling Mating (Heterozygote x Wild-type or Heterozygote) |
References | Mech. Dev., 108, 213-216 (2001). 11578878 Cancer Res., 52, 2304-2309 (1992). 1559233 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter |
Ordering Information | |
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Donor DNA | |
Research application | Developmental Biology Research Immunology and Inflammation Research Mouse Models for Human Disease Neurobiology Research Reproductive Biology Research Sensorineural Research |
Specific Term and Conditions | No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.) |
Depositor | Yukihiko Kitamura (Osaka University) |
Strain Status | Frozen embryos |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |