Strain Information | |
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Image | |
BRC No. | RBRC00432 |
Type | Spontaneous Mutation |
Species | Mus musculus |
Strain name | RLC/Stm |
Former Common name | RLC/Stm |
H-2 Haplotype | |
ES Cell line | |
Background strain | RLC/Stm |
Appearance | albino |
Strain development | Spontaneous mutation originally arose in CXSN/A strain. The mutant mice were bred with a BALB/cHeA and then maintained by inbreeding. |
Strain description | rlc, Rupture of Lens Cataract. Spontaneous recessive mutation arose in CXSN/A mice. The mutation as a deletion of 27 bp at the end of 15th of Dock5 gene. |
Colony maintenance | |
References | Graefe's Arch. Clin. Exp. Ophthalmol., 238, 970-978 (2000). 11196360 Genomics, 36, 553-554 (1996). 8884285 Exp. Eye Res., 64, 107-113 (1997). 9093026 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter |
Ordering Information | |
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Donor DNA | |
Research application | Mouse Models for Human Disease Sensorineural Research |
Specific Term and Conditions | No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.) |
Depositor | Yoshibumi Matsushima (Saitama Cancer Center) |
Strain Status | Frozen embryos |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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Hiai H, Tsuruyama T, Yamada Y. Pre-B lymphomas in SL/Kh mice: a multifactorial disease model. Cancer Sci 94(10) 847-50(2003) 14556656 Omi N, Kiyokawa E, Matsuda M, Kinoshita K, Yamada S, Yamada K, Matsushima Y, Wang Y, Kawai J, Suzuki M, Hayashizaki Y, Hiai H. Mutation of Dock5, a member of the guanine exchange factor Dock180 superfamily, in the rupture of lens cataract mouse. Exp Eye Res 86(5) 828-34(2008) 18396277 |