Strain Data Sheet

RBRC00816

Strain Information

Image
BRC No.RBRC00816
TypeTargeted Mutation and TransgeneCartagena
SpeciesMus musculus
Strain nameB6;129P2(B6)-Prnp<tm1Ito> Tg(CAG-PRNP)1Ondr/Rbrc
Former Common namescimitar-homed oryx PrP mouse
H-2 Haplotype
ES Cell lineE14 [129P2/OlaHsd]
Background strain
Appearance
Strain development
Strain description
Colony maintenance
ReferencesIntervirology, 44, 359-363 (2001). 11805443

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
PrnPprion protein2PrnP<tm1Ito>targeted mutation 1, Shigeyoshi ItoharaPrP, PrPC, Sinc, +Prnp, CD230, PrPSc, Prn-i, Prn-p, PrP

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)2neo; neomycin;mouse phosphoglycerate kinase promoter (PGK promoter)

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
PRNPprion protein (Orix)UNPRNPPrP, PrPC, Sinc, +Prnp, CD230, PrPSc, Prn-i, Prn-p, PrPCAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA)

Ordering Information

Donor DNACAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA), scimitar-homed oryx PrP cDNA, E. coli neo, rabbit beta-globin splicer, 3 UTR, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, mouse PrnP genomic DNA
Research applicationCardiovascular Research
Mouse Models for Human Disease
Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
DepositorTakashi Onodera (The University of Tokyo)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  4. CAGGS MTA (English)
  5. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data