Strain Information | |
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Image | |
BRC No. | RBRC06139 |
Type | Transgene |
Species | Mus musculus |
Strain name | C57BL/6-Tg(Fabp4-Serpina12)1 |
Former Common name | Vaspin Tg#1, B6-Serpina12 Tg#1 |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6JJcl |
Appearance | |
Strain development | Developed by Jun Wada, Department of Medicine and Clinical Science, Okayama University and Yoichiro Iwakura, Institute of Medical Sciences, University of Tokyo in 2005. C57BL/6J background. |
Strain description | Vaspin (Serpina12) gene transgenic mice. These mice express the mouse Vaspin gene under the control of the aP2 promoter. Tg mice are protected from diet-induced obesity, glucose intolerance, and hepatic steatosis. |
Colony maintenance | Carrier x Noncarrier [C57BL/6JJcl] |
References | Diabetes, 61, 2823-2832, (2012). 22837305 Circ Res., 112, 771-780 (2013). 23307819 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter GHGrowth hormone polyA (human)UNGH Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter HBB2rabbit beta-globin intronUNHBB2 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Serpina12serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12UNSerpina12mouse fatty acid binding protein 4, adipocyte promoter |
Ordering Information | |
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Donor DNA | mouse fatty acid binding protein 4 (Fabp4) adipocyte promoter, mouse SERPINA12 (vaspin) gene cDNA, rabbit beta-globin intron, human GH polyA signal |
Research application | Diabetes and Obesity Research Metabolism Research Mouse Models for Human Disease covid19_progression |
Specific Term and Conditions | No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.) |
Depositor | Jun Wada (Okayama University) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |