Strain Information | |
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Image | |
BRC No. | RBRC09238 |
Type | Transgene |
Species | Mus musculus |
Strain name | C57BL/6-Tg(CAG-CCND1)14Hzi |
Former Common name | D1b14F, B6-CAG-CCND1 Tg#14 |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6JJcl |
Appearance | |
Strain development | Developed by Hirokazu Inoue, Shiga University of Medical Science and Gen Kondoh, Institute for Frontier Medical Science. The transgene was injected into the pronuclei of C57BL/6 fertilized eggs. |
Strain description | Cyclin D1b transgenic mice in which the human cyclin D1b transgene was driven by a pCAGGS promoter. Tg females develop rectal tumoers within 4 to 12 months after birth (female: 60%, male: 4%). The transgene was inserted into the intron region in chromosome 7 (7qA1). |
Colony maintenance | Carrier x Noncarrier [C57BL/6JJcl] |
References | Carcinogenesis, 35, 227-236 (2014). 23975835 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter CCND1cyclin D1 (human)7CCND1CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter FLAGFLAG tag (synthetic)7FLAG |
Ordering Information | |
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Donor DNA | CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA), Human Cyclin D1b gene cDNA, FLAG-tag |
Research application | Cancer Research Cell Biology Research Mouse Models for Human Disease |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. |
Depositor | Hirokazu Inoue (Shiga University of Medical Science) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |