Strain Data Sheet
Data update: Aug 27, 2014
Health Certificate   PCR Protocol   Thawing Method
embryos / sperm >
  Mouse Marking
RBRC No. RBRC00357  
Type Targeted MutationCartagena   4wks,♂
Species Mus musculus  
Strain name BALB/cA-TgH(Tnc)-Foxn1nu  
Former Common name BALB/cA-Tnc-nude  
H-2 Haplotype No Data  
Background strain BALB/cA  
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Dr. M. Kusakabe, Tsukuba Life Science Center, Institute of Physical and Chemical Research (RIKEN).  
Strain description C.Cg-Tnc<tm1Sia> Foxn1<nu>. Mice lacking tenascin C gene with a nude mutation. This strain is useful for studying the function of tenascin C in tumor proliferation and metastasis, neoangiogenesis, interoganizartional interation, and transplantation of human tumor.  
Health Certificate No Data  
Gene Details
Promoter No Data  
 1 Symbol Foxn1  
Symbol name forkhead box N1  
Chromosome 11  
Common name D11Bhm185e, Hfh11, whn  
Symbol description No Data  
 2 Symbol Tnc  
Symbol name tenascin C  
Chromosome 4  
Common name Tnc; tenascin C, Hxb, Ten, TN-C, AI528729  
Symbol description No Data  
 3 Symbol lacZ  
Symbol name beta-galactosidase (E. coli)  
Chromosome 4  
Common name No Data  
Symbol description E. coli beta galactosidase  
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)  
 4 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 4  
Common name neo; neomycin;  
Symbol description No Data  
References Am J Pathol. 1998 May;152(5):1237-45.
Anticancer Res. 1998 Sep-Oct;18(5C):3817-91.
Biochem Biophys Res Commun. 1996 Apr 5;221(1):151-6.
Biochem Biophys Res Commun. 1997 Feb 13;231(2):356-9.
Biochem Biophys Res Commun. 2002 Feb 1;290(4):1220-7.
Exp Mol Pathol. 2002 Jun;72(3):186-95.
Gene. 1991 Aug 15;104(2):177-85.
Genes Dev. 1992 Oct;6(10):1821-31.
Invest Ophthalmol Vis Sci. 1999 May;40(6):1071-80.
J Comp Neurol. 2001 Feb 19;430(4):485-500.
J Invest Dermatol. 1998 Dec;111(6):930-5.
J Neurosci. 1995 Mar;15(3 Pt 1):1971-83.  

Research applications No Data  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Am. J. Pathol., 152, 1237-1245 (1998). J. Invest. Dermatol., 111, 930-935 (1998). Invest. Ophthalmol. Visual. Sci., 40, 1071-1080 (1999).  
Additional information
 1 No Data  
 2 Genotyping protocol <PCR>  
Depositor RIKEN, BioResource Center   
Strain Status /
(Expected delivery)

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