Strain Data Sheet
Data update: Aug 27, 2014
Health Certificate   PCR Protocol   Thawing Method
embryos / sperm >
  Mouse Marking
RBRC No. RBRC00690  
Type Targeted MutationCartagena   wks
Species Mus musculus  
Strain name beta-galactosidase Knockout mice  
Former Common name No Data  
H-2 Haplotype No Data  
Donor strain (C57BL/6 x CBA)F1 via TT2 ES cell line  
Background strain C57BL/6J  
 1 Appearance black  
Genotype No Data  
Strain development 1997, Kunihiko Suzuki, M.D.
Departments of neurology and Psychiatry, University of North Carolina, Chapel Hill, NC 27599-7250, U.S.A.  
Strain description Neurobiology Research, Metabolic Defects, Lysosomal Storage Disease  
Colony maintenance Heterozygote X Heterozygote  
Health Certificate No Data  
Gene Details
Promoter No Data  
 1 Symbol Glb1  
Symbol name galactosidase, beta 1  
Chromosome 9  
Common name Bge, Bgl, Bgl-e, Bgl-s, Bgl-t, Bgs, Bgt  
Symbol description No Data  
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)  
 2 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 9  
Common name neo; neomycin;  
Symbol description No Data  
References Hum Mol Genet. 1997 Feb;6(2):205-11.  
Generalized CNS disease and massive GM1-ganglioside accumulation in mice defective in lysosomal acid beta-galactosidase.
Research applications Metabolism Research,
Neurobiology Research  
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)  
Additional information
 1 No Data  
 2 Genotyping protocol <PCR>  
Depositor Matsuda, Junko (The University of Tokushima)  Matsuda, Junko 
Strain Status /
(Expected delivery)

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