|
RBRC No. |
RBRC00690
|
|
Type |
Targeted Mutation |
 |
|
Species |
Mus musculus |
|
Strain name |
beta-galactosidase Knockout mice |
|
Former Common name |
No Data |
|
H-2 Haplotype |
No Data |
|
Donor strain |
(C57BL/6 x CBA)F1 via TT2 ES cell line |
|
Background strain |
C57BL/6J |
|
Appearance |
| 1 |
Appearance |
black |
| Genotype |
No Data |
|
Strain development |
1997, Kunihiko Suzuki, M.D.
Departments of neurology and Psychiatry, University of North Carolina, Chapel Hill, NC 27599-7250, U.S.A. |
|
Strain description |
Neurobiology Research, Metabolic Defects, Lysosomal Storage Disease |
|
Colony maintenance |
Heterozygote×Heterozygote |
|
Animal health report |
No Data |
|
Gene Details |
|
Promoter |
No Data |
| 1 |
Symbol |
Glb1 |
| Symbol name |
galactosidase, beta 1 |
| Chromosome |
9 |
| Common name |
Bge, Bgl, Bgl-e, Bgl-s, Bgl-t, Bgs, Bgt |
| Symbol description |
No Data |
|
Promoter |
mouse phosphoglycerate kinase promoter (PGK promoter) |
| 2 |
Symbol |
neo |
| Symbol name |
neomycin resistance gene (E. coli) |
| Chromosome |
9 |
| Common name |
neo; neomycin; |
| Symbol description |
No Data |
|
References |
Hum Mol Genet. 1997 Feb;6(2):205-11. Generalized CNS disease and massive GM1-ganglioside accumulation in mice defective in lysosomal acid beta-galactosidase. |
|
Research applications |
Metabolism Research,
Neurobiology Research |
|
Specific Term and Conditions |
No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.) |
|
Additional information |
|
1 |
No Data |
|
2 |
Genotyping protocol <PCR> |
|
Depositor |
Matsuda, Junko (The University of Tokushima)  |
|
Strain Status /
Availability
(Expected delivery) |
|
