Strain Information | |
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Image | |
BRC No. | RBRC00753 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6;129P2-Sema4d<tm1Kik>/Rbrc |
Former Common name | CD100 Knockout mice |
H-2 Haplotype | |
ES Cell line | E14.1 [129P2/OlaHsd] |
Background strain | |
Appearance | |
Strain development | |
Strain description | |
Colony maintenance | |
References | Immunity, 13, 633-642 (2000). 11114376 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Sema4dsema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D13Sema4d<tm1Kik>targeted mutation 1, Hitoshi KikutaniCD100, coll-4, M-sema G, Semacl2, SEMAJ, Semaj, semaphorin H, Semcl2 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)13neo; neomycin;herpes simplex virus thymidine kinase promoter (HSV tk promoter) |
Ordering Information | |
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Donor DNA | herpes simplex virus thymidine kinase promoter (HSV tk promoter), E. coli neo, mouse CD100 genomic DNA |
Research application | |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Immunity, 13, 633-642 (2000). |
Depositor | Hitoshi Kikutani (Osaka University) |
Strain Status | Frozen embryos |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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Zhang C, Qiao H, Guo W, Liu Y, Yang L, Liu Y, Jin B, Fu M, Wang G, Li W. CD100-plexin-B1 induces epithelial-mesenchymal transition of head and neck squamous cell carcinoma and promotes metastasis. Cancer Lett 455 1-13(2019) 30981760 Xiao C, Luo Y, Zhang C, Zhu Z, Yang L, Qiao H, Fu M, Wang G, Yao X, Li W. Negative regulation of dendritic cell activation in psoriasis mediated via CD100-plexin-B2. J Pathol 250(4) 409-419(2020) 31943215 Zhu Z, Luo Y, Yu J, Gao J, Zhang Y, Xiao C, Zhang C, Wang G, Liu Y, Fu M, Yao X, Li W. Sema4D is required in both the adaptive and innate immune responses of contact hypersensitivity. Mol Immunol 78 98-104(2016) 27614265 |