Strain Data Sheet

RBRC00849

Strain Information

Image
BRC No.RBRC00849
TypeSpontaneous Mutation Congenic
SpeciesMus musculus
Strain nameB6;KOR1-Traf3ip2<adjm>
Former Common nameB6.NAD
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Appearanceblack
Strain developmentDeveloped by Dr. Yoshibumi Matsushima, Research Institute for Clinical Oncology, Saitama Cancer Center.
Strain descriptionC57BL/6 congenic strain having a sponatenous mutation found in a colony of the KOR inbred strain derived from Japanese wild mice. Homozygous mutant mice show high levels of serum IgE and an atopic dermatitis (AD)-like skin disease. The pehotype of this strain is less than on the KOR orinigal strain. Homozygous mutant mice are viable and fertile.
Colony maintenance
ReferencesImmunopharmacol Immunotoxicol, 37, 202-206 (2015). 25578901
J. Immunol., 185, 2340-2349 (2010). 20660351
Exp. Anim., 61, 25-33 (2012). 22293669

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Traf3ip2TRAF3 interacting protein 210Traf3ip2<adjm>atopic dermatitis from Japanese mice

Ordering Information

Donor DNA
Research applicationDermatology Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Immunol., 185, 2340-2349 (2010). Immunopharmacol Immunotoxicol, 37, 202-206 (2015).
DepositorYoshibumi Matsushima (Saitama Cancer Center)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data