Strain Information | |
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Image | |
BRC No. | RBRC00866 |
Type | Transgene |
Species | Mus musculus |
Strain name | C57BL/6N-Tg(CAG-NR4A3)N2/Rbrc |
Former Common name | C57BL/6-TgN(act-Nor-1)N2 |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6NCrlCrlj |
Appearance | |
Strain development | Developed by Genox Research, Inc. in 2002. The transgene was injected into the pronucleous of C57BL/6N fertilized eggs. |
Strain description | These transgenic mice express human NOR-1 for neuron derived orphan receptor, (GenBank accesion No. D78579) under the control of the CAG promoter. Expression level of the transgene in brain is high in line N1 (RBRC00865), subsequently in line N3 (RBRC00867), less in line N2 (RBRC00866). Expression of the transgene in spleen was also observed in line N1. |
Colony maintenance | |
References |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter NR4A3neuron derived orphan receptor (human)UNNR4A3neuron derived orphan receptor, human Nor-1CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter attB1attachment siteUN Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter attB2attachment siteUN |
Ordering Information | |
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Donor DNA | CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA), Human NOR-1 cDNA for neuron derived orphan receptor, attB1, attB2 |
Research application | |
Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. |
Depositor | Ryoichi Hashida (Eisai Co., Ltd.) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |