Strain Information | |
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Image | |
BRC No. | RBRC01271 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6;129S6-Grm1<tm1Nak>/NakRbrc |
Former Common name | mGliR1TL36, B6;129-Grm1<tm(D854T)>/mGluR1TL36 |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6J |
Appearance | |
Strain development | Developed by Drs. Sato Masaaki and Shigetada Nakanishi, Kyoto University Faculty of Medicine in 2004. |
Strain description | Grm1 (glutamate receptor, metabotropic 1)(mGluR1) knock-in mice, in which aspartate at position 854 was replaced with threonibe (termed D854T). D854T mutant mice homozygous show no obvious behavioural abnormality. |
Colony maintenance | |
References | Eur. J. Neurosci., 20, 947-955 (2004). 15305863 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Grm1glutamate receptor, metabotropic 110Grm1<tm1(D854T)>targeted mutation 1, (D854T)Gprc1a, Grm1, mGluR1 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP10loxP |
Ordering Information | |
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Donor DNA | mouse glutamate receptor, metabotropic 1 genomic DNA, phage P1 loxP |
Research application | Cell Biology Research Neurobiology Research |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Eur. J. Neurosci., 20, 947-955 (2004).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. |
Depositor | Shigetada Nakanishi (Kyoto University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |