Strain Data Sheet

RBRC01272

Strain Information

Image
BRC No.RBRC01272
TypeSpontaneous Mutation
SpeciesMus musculus
Strain nameBALB/c-elap/Rbrc
Former Common nameelap mouse
H-2 Haplotype
ES Cell line
Background strainBALB/c
Appearancealbino [A/A b/b c/c]
Strain developmentDeveloped by Dr. Sunao Aso at Chemical Inspection and Testing Iinstitute, Japan.
Strain descriptionEye lens aplasia. Autosomal recessive mutation which arose in the BALB/c breeding colony. Homozygous mutant mice for eye lens aplasia have microphthalmia, aphakia, absence of the anterior chamber, dystrophy of the cornea and vitreous body, and retinal disorganization.
Colony maintenanceSibling MatingHomozygous mutant mice are viable and fertile.
ReferencesTeratology, 61, 262-272 (2000). 10716744
Teratology, 58, 44-53 (1998). 9787405
Lab. Anim. Sci., 45, 41-46 (1995). 7752613
Exp. Anim., 50, 97-98 (2001). 11326432

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
elapeye lens aplasia2elap<elap>eye lens aplasialap

Ordering Information

Donor DNA
Research applicationCancer Research
Cell Biology Research
Specific Term and ConditionsIn publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
DepositorSunao Aso (Chemicals Evaluation and Research Institute)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved embryos (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data