Strain Information | |
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Image | |
BRC No. | RBRC01476 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | MRL.129P2(B6)-Fas<tm1Osa>/OsaRbrc |
Former Common name | MRL Fas-KO |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Drs. Masashi Adachi and Shigekazu Nagata at Osaka University Medical School in 1995. |
Strain description | |
Colony maintenance | Backcross to MRL/MpJJmsSlc (Heterozygote x C57BL/6NCrlCrlj) |
References | Nat. Genet., 11(3), 294-300 (1995). 7581453 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter FasFas (TNF receptor superfamily member)19Fas<tm1Osa>targeted mutation 1, Osaka University Medical SchoolAPO-1, CD95, TNFR6, Tnfrsf6 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter lacZbeta-galactosidase (E. coli)19 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)19neo; neomycin;mouse phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
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Donor DNA | mouse Fas genomic DNA, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, E. coli lacZ |
Research application | Apoptosis Research Immunology and Inflammation Research |
Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Nature Genetics, 11, 294-300 (1995).RECIPIENT may only use the BIOLOGICAL RESOURCE for non-commercial academic research purpose. The RECIPIENT should negotiate with the DEPOSITOR in the case of application for any patents or commercial use with the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Shigekazu Nagata (Kyoto University) |
Strain Status | Frozen embryos |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |