Strain Information | |
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Image | |
BRC No. | RBRC01508 |
Type | Transgene |
Species | Mus musculus |
Strain name | C57BL/6-Tg(Camk2a-cre,-tTA)1Tyag/TyagRbrc |
Former Common name | CaM-Cre 1 mice |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | black [a/a B/B C/C] |
Strain development | Developed by Drs. Makoto Sanbo and Takeshi Yagi, National Institute for Physiological Sciences, Japan. |
Strain description | This transgenic mouse expresses the cre-recombinase under the control of the calcium/calmodulin-dependent protein kinase II alpha promoter. This strain can be used to make an inducible knock-out by crossing with the other genetically-engineeered mice that have floxed genes. |
Colony maintenance | Backcross to C57BL/6 (Hemizygote x C57BL/6NCrlCrlj) |
References |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter GHGrowth hormone polyA (human)UNGH Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter IRESinternal ribosomal entry site (EMCV)UNinternal ribosomal entry site from EMCV Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter crePhage P1 Cre recombinaseUNcremouse Camk2a promoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter tTAtTA (E. coli tet repressor (TetR), herpes simplex virus (HSV) VP16 activation domain)UNtTAE. coli tet repressor (TetR), herpes simplex virus (HSV)VP16 activation domain |
Ordering Information | |
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Donor DNA | mouse CaM Kinase2 promoter, P1 phage hnCre recombinase, E. coli tet repressor (TetR), herpes simplex virus (HSV)VP16 activation domain, Encephalomyocarditis virus (EMCV) internal ribosomal entry site (ires), human Growth Hormone-poly A |
Research application | Cell Biology Research Cre/loxP system Tet system |
Specific Term and Conditions | 1. The RECIPIENT should negotiate with Dr. Takeshi Yagi and Makoto Sanbo in the case of application for any patents with the results from the use of the BIOLOGICAL RESOURCE. 2. The RECIPIENT should contact with Dr. Takeshi Yagi and Makoto Sanbo in regard to co-authorship. |
Depositor | Kazuhiro Ikenaka (National Institute for Physiological Sciences) |
Strain Status | Frozen embryos |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved embryos (within 1 month) |
Additional Info. | Genotyping protocol -PCR- Necessary documents for ordering:
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BRC mice in Publications |
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No Data |