Strain Data Sheet
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Data update: Jan 30, 2017
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RBRC No. RBRC01828  
Type Transgene CongenicCartagena  
Species Mus musculus  
Strain name B6.Cg-Tg(CAG-Cre)CZ-MO2Osb  
Former Common name CAG-cre  
H-2 Haplotype No Data  
Background strain C57BL/6  
Appearance
 1 Appearance black  
Genotype a/a B/B C/C  
Strain development Developed by Masaru Okabe, Research Institute for Microbial Diseases, Osaka University in 2003. The transgene was injected into the pronuclei of B6D2F2 fertilized eggs. The mice were backcrossed C57BL/6N.  
Strain description These transgenic mice express Cre recombinase gene under the control of CAG promoter. This strain can be used to make an inducible knock-out by crossing with the other genetically-engineered mice that have a loxP site-flanked sequence of interest. The recombination occurs in all over the body.  
Colony maintenance Carrier x Noncarrier [C57BL/6NCrSlc]  
Health Report
Gene Details
Promoter CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA)  
 1 Symbol cre  
Symbol name Phage P1 Cre recombinase  
Chromosome UN  
Common name No Data  
Symbol description No Data  
References Biochem Biophys Res Commun. 2004 Aug 20;321(2):275-9.  
Lineage-specific cell disruption in living mice by Cre-mediated expression of diphtheria toxin A chain.
Research applications Cre/loxP system  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Biochem. Biophys. Res. Commun., 321, 275-279 (2004).
RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University (http://www.uic.osaka-u.ac.jp/en/index.html). The RECIPIENT which wants to use the BIOLOGICAL RESOURCE even after five years must obtain a written consent from the DEPOSITOR again.  
Additional information
 1 Lab HP  
 2 Genetic Background  
 3 Genotyping protocol <PCR>  
Depositor Okabe, Masaru (Osaka university)  Okabe, Masaru 
Strain Status /
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