Strain Information | |
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Image | |
BRC No. | RBRC01830 |
Type | Transgene Congenic |
Species | Mus musculus |
Strain name | B6.Cg-Tg(Blimp1-RFP)1Rbrc |
Former Common name | Blimp1-RFP#1 |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Drs. Michihiko Sugimoto and Kuniya Abe, RIKEN BioResource Center in 2005. |
Strain description | This transgenic mouse expresses RFP under the control of Blimp1 promoter. Expression intensity display high in line 1 (RBRC01830), weak in line 2 (RBRC01831), line 3 (RBRC01832) and line 4 (RBRC01833) (expression of line 4 is higher than line 2 and 3). Tg Homozygous mice of line 1 are embryonic lethal. |
Colony maintenance | |
References | PLoS Genet., 3, e116 (2007). 17676999 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) siteUNFrt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter GHGrowth hormone polyA (Bovine)UNGH Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter mRFPmonomeric Red Fluorescent Protein (Discosoma sp.)UNmRFPmouse Blimp1 promoter region, bovine growth hormone poly A |
Ordering Information | |
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Donor DNA | mouse Blimp1 genomic DNA (BAC clone RP23-1D12), mRFP cDNA (Discosoma sp.), bovine growth hormone poly A, yeast FRT (flipase recombination target) site |
Research application | Fluorescent Proteins/lacZ System |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. PLoS Genet., 3, e116 (2007). |
Depositor | Kuniya Abe (RIKEN) |
Strain Status | Frozen embryos |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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Mochizuki K, Hayashi Y, Sekinaka T, Otsuka K, Ito-Matsuoka Y, Kobayashi H, Oki S, Takehara A, Kono T, Osumi N, Matsui Y. Repression of Somatic Genes by Selective Recruitment of HDAC3 by BLIMP1 Is Essential for Mouse Primordial Germ Cell Fate Determination. Cell Rep 24(10) 2682-2693.e6(2018) 30184502 Cao L, Shitara H, Sugimoto M, Hayashi J, Abe K, Yonekawa H. New evidence confirms that the mitochondrial bottleneck is generated without reduction of mitochondrial DNA content in early primordial germ cells of mice. PLoS Genet 5(12) e1000756(2009) 19997484 |