Strain Information | |
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Image | |
BRC No. | RBRC01924 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6;129(Cg)-Zeb2<tm1.1Yhi> |
Former Common name | SIP1 flox (ex7), B6;129-Zfhx1b<tm1.1Yhi> |
H-2 Haplotype | |
ES Cell line | R1 [(129X1/SvJ x 129S1/Sv)F1-Kitl<+>] |
Background strain | |
Appearance | black [a/a B/B C/C] |
Strain development | Developed by Dr. Yujiro Higashi, Osaka University in 2002. |
Strain description | Smad-interacting protein 1, SIP1 is a member of the ZFHX1 family of two-handed zinc finger nuclear factors that are associated with epithelial mesenchymal transitions (EMT) during development. Conditional SIP1 deficient mice can be generated bycrossing with tissue specific Cre transgenic mice. |
Colony maintenance | Backcross to C57BL/6Cr |
References | Genesis, 32, 82-84 (2002). 11857784 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Zfhx1bzinc finger homeobox 1b2Zfhx1b<tm1.1Yhi>targeted mutation 1.2, Yujiro Higashi9130203F04Rik, D130016B08Rik, mKIAA0569, SIP1, Zfx1b Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP2loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP2loxP |
Ordering Information | |
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Donor DNA | phage P1 loxP sites, mouse Zfhx1b genomic DNA |
Research application | Cre/loxP system |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genesis, 32, 82-84 (2002). The RECIPIENT should consult with the DEPOSITOR in the case of application for any patents or commercial use with the results derived from the use of the BIOLOGICAL RESOURCE. The RECIPIENT should consult with the DEPOSITOR on the authorship upon publications of the results obtained from the use of the BIOLOGICAL RESOURCE. The authorship should be considered in accordance to generally accepted practices and decided through agreement between the RECIPIENT and the DEPOSITOR/DEVELOPER. The RECIPIENT of BIOLOGICAL RESOURCE should obtain prior permission from Dr. Danny Huylebroeck (Erasmus University Medical Center (Erasmus MC), The Netherlands). |
Depositor | Yujiro Higashi (Osaka University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |