Strain Information | |
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Image | |
BRC No. | RBRC02139 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | STOCK Cnga2<tm1Mom> Olfr151<tm25Mom> Pcdha<tm3Tyag>/TyagRbrc |
Former Common name | OCNC1/M71-LacZ/BdAB |
H-2 Haplotype | |
ES Cell line | W9.5 [129S1/Sv-Oca2<+> Tyr<+> Kitl<+>] |
Background strain | |
Appearance | |
Strain development | Developed by Takeshi Yagi, Graduate School of Frontier Biosciences, Osaka University. The mutant mice were generated by crossing with CNR delta CR (BdAB) (RBRC01688) (Takeshi Yagi, Graduate School of Frontier Biosciences, Osaka University) and OCNC1 KO and M71-lacZ mice (Peter Monbaerts, The Rockefeller University). |
Strain description | OCNC1 (Cnga2) knockout, CNR (Pcdha) delta CR mutant and M71 (Olfr151) gene ires-taulacZ knock-in triple mutant mice. |
Colony maintenance | Pcdha: Homozygote x Homozygote; Olfr151: Homozygote x Homozygote; Cnga2: Heterozygote (female) x Wild-type (male) |
References | Neuron, 35, 681-696 (2002). 12194868 Neuron. 26(1):81-91 (2000). 10798394 Mol Cell Neurosci, 38, 66-79 (2008). 18353676 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Pcdhaprotocadherin alpha cluster18Pcdha<tm3Tyag>targeted mutation 3, Takeshi YagiA830022B16Rik, Cnr7, Crnr7 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP18loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Olfr151olfactory receptor 1519Olfr151<tm25Mom>targeted mutation 25, Peter MombaertsGA_x6K02T2PVTD-31408136-31407207, M71, MOR171-2 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter IRESinternal ribosomal entry site (EMCV)9 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter lacZbeta-galactosidase (E. coli)9 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP9loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter taubovine tau protein cDNA9tau Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Cnga2cyclic nucleotide gated channel alpha 2XCnga2<tm1Mom>targeted mutation 1, Peter MombaertsCnca, Cncg4, OCNC1 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxPXloxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxPXloxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)Xneo; neomycin;mouse phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
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Donor DNA | Phage P1 loxP sites, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, Encephalomyocarditis virus (EMCV) internal ribosomal entry site (ires), E. coli lacZ, bovine tau cDNA, mouse Olfr151 genomic DNA, mouse Pcdha genomic DNA, mouse Cnga2 genomic DNA |
Research application | Cre/loxP system Fluorescent Proteins/lacZ System Neurobiology Research |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior consent on use of it from Professor Peter Monbaerts, The Rockefeller University. If the RECIPIENT's research results in an invention based on the BIOLOGICAL RESOURCE, the RECIPIENT must contact DEPOSITOR to negotiate the treatment of such invention. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, the RECIPIENT must obtain a prior written consent from the DEPOSITOR. The RECIPIENT, which wishes to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research, is requested to enter into a Material Transfer Agreement with Osaka University. |
Depositor | Takeshi Yagi (Osaka University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |