Strain Information | |
---|---|
Image | |
BRC No. | RBRC02260 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.129S-Trp53<tm2Mok> |
Former Common name | p53KO, PFZ, PFZ632, B6-p53 KO |
H-2 Haplotype | |
ES Cell line | CCE/EK.CCE [129S/SvEv-Gpi1<c>] |
Background strain | C57BL/6JJcl |
Appearance | black [a/a B/B C/C] |
Strain development | Developed by Motoya Katsuki, National Institutes of Natural Sciences (Medical Institute of Bioregulation, Kyushu University). |
Strain description | p53 (Trp53) gene knockout mice (lacZ reporter). |
Colony maintenance | Heterozygote x Wild-type [C57BL/6JJcl] |
References | Biochem. Biophys. Res. Commun., 202, 830-837 (1994). 8048955 |
Health Report | |
---|---|
Examination Date / Room / Rack |
Gene | |
---|---|
Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter lacZbeta-galactosidase (E. coli)11 |
Ordering Information | |
---|---|
Donor DNA | E coli lacZ (beta galactosidase), mouse p53 genomic DNA |
Research application | Cancer Research Cell Biology Research Fluorescent Proteins/lacZ System Immunology and Inflammation Research Mouse Models for Human Disease |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Biochem. Biophys. Res. Commun., 202, 830-837 (1994). In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Toshikuni Sasaoka (Niigata University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
---|
No Data |