Strain Information | |
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Image | |
BRC No. | RBRC02268 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.129S4-Sgcb<tm1Oza> |
Former Common name | BSG-KO (C57BL/6J), B6-Sgcb KO |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6JJcl |
Appearance | black [a/a B/B C/C] |
Strain development | Developed by Toshikuni Sasaoka, National Institutes of Natural Sciences (National Institute of Neuroscience, National Center of Neurology and Psychiatry). |
Strain description | Beta-sarcoglycan (Sgcb) gene knockout mice. Sgcb is an integral component of the dystrophin-glycoprotein complex. Homozygous mutant mice show progressive muscular dystrophy with extensive degeneration and regeneration. |
Colony maintenance | Heterozygote x Wild-type [C57BL/6JJcl] |
References | Hum Mol Genet. 1999 8(9):1589-98. 10441321 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Sgcbsarcoglycan, beta (dystrophin-associated glycoprotein)5Sgcb<tm1Oza>targeted mutation 1, Eijiro Ozawa Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)5neo; neomycin; |
Ordering Information | |
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Donor DNA | E coli neo, mouse beta-sarcoglycan (BSG) genomic DNA, mouse phosphoglycerate kinase promoter (PGK promoter) |
Research application | |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Hum. Mol. Genet., 8, 1589-1598 (1999). In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Toshikuni Sasaoka is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Toshikuni Sasaoka (Niigata University) |
Strain Status | Frozen embryos |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |