Strain Information | |
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Image | |
BRC No. | RBRC02332 |
Type | Transgene Congenic |
Species | Mus musculus |
Strain name | B6.Cg-Tg(Drd2-YFP)364-5 |
Former Common name | B6.Cg-Tg(Drd2-YFP)364-5 |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6JJcl |
Appearance | black [a/a B/B C/C] |
Strain development | Developed by Dr. Kazuto Kobayashi, Fukushima Medical University School of Medicine in 2007. The Drd2-YFP transgene was injected into the pronuclei of C57BL/6J fertilized eggs. |
Strain description | This transgenic strain expresses YFP under the control of rat dopamine receptor 2 gene promoter. |
Colony maintenance | Hemizygote x Non carrier [C57BL/6JJcl] |
References | Neuron, 89 (3) 550-565 (2016). 26804993 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter YFPYellow Fluorescent Protein (Aequorea victoria)UNYFPrat Drd2 promoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter poly ASV40 polyAUNpoly A |
Ordering Information | |
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Donor DNA | Rat Drd2 promoter (Rat BAC clone), Jellyfish YFP cDNA、SV40 early gene polyA signal |
Research application | Fluorescent Proteins/lacZ System Neurobiology Research |
Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Neuron, 89 (3) 550-565 (2016).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT shall contact the DEPOSITOR (Dr. Kazuto Kobayasi, kazuto@fmu.ac.jp) about the use of the BIOLOGICAL RESOURCE in advance. |
Depositor | Kazuto Kobayashi (Fukushima Medical University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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Faruk MO, Tsuboi D, Yamahashi Y, Funahashi Y, Lin YH, Ahammad RU, Hossen E, Amano M, Nishioka T, Tzingounis AV, Yamada K, Nagai T, Kaibuchi K. Muscarinic signaling regulates voltage-gated potassium channel KCNQ2 phosphorylation in the nucleus accumbens via protein kinase C for aversive learning. J Neurochem 160(3) 325-341(2022) 34878647 Nagai T, Nakamuta S, Kuroda K, Nakauchi S, Nishioka T, Takano T, Zhang X, Tsuboi D, Funahashi Y, Nakano T, Yoshimoto J, Kobayashi K, Uchigashima M, Watanabe M, Miura M, Nishi A, Kobayashi K, Yamada K, Amano M, Kaibuchi K. Phosphoproteomics of the Dopamine Pathway Enables Discovery of Rap1 Activation as a Reward Signal In Vivo. Neuron 89(3) 550-65(2016) 26804993 Bin Saifullah MA, Nagai T, Kuroda K, Wulaer B, Nabeshima T, Kaibuchi K, Yamada K. Cell type-specific activation of mitogen-activated protein kinase in D1 receptor-expressing neurons of the nucleus accumbens potentiates stimulus-reward learning in mice. Sci Rep 8(1) 14413(2018) 30258218 |