|
RBRC No. |
RBRC02349
|
|
Type |
Targeted Mutation |
 |
|
Species |
Mus musculus |
|
Strain name |
C57BL/6-Fabp7<tm1(cre)Ksak> |
|
Former Common name |
BFABP-Cre |
|
H-2 Haplotype |
No Data |
|
Background strain |
C57BL/6 |
|
Appearance |
| 1 |
Appearance |
No Data |
| Genotype |
No Data |
|
Strain development |
Developed by Mika Tsujita, Rie Natsume and Kenji Sakimura, Brain Research Institute, Niigata University in 2004. RENKA ES cells derived from C57BL/6NCrj were used. C57BL/6N background. |
|
Strain description |
Fabp7 Cre knock-in mice. A Cre sequence was integrated into the start methionine site of the B-FABP gene at an in-frame position. A non-coding and pgk-neo cassette sequence are located downstream from Cre. The pgk-neo cassette can be removed, as it has an frt sequence on both sides. |
|
Colony maintenance |
Heterozygote x Wild-type [C57BL/6NCrlCrlj] |
|
Animal health report |
No Data |
|
Gene Details |
|
Promoter |
No Data |
| 1 |
Symbol |
Fabp |
| Symbol name |
fatty acid binding protein 7, brain |
| Chromosome |
10 |
| Common name |
B-FABP, Blbp |
| Symbol description |
No Data |
| 2 |
Symbol |
cre |
| Symbol name |
Phage P1 Cre recombinase |
| Chromosome |
10 |
| Common name |
No Data |
| Symbol description |
No Data |
| 3 |
Symbol |
frt |
| Symbol name |
yeast FRT (flippase recombination target) sites |
| Chromosome |
10 |
| Common name |
No Data |
| Symbol description |
No Data |
| 4 |
Symbol |
poly A |
| Symbol name |
mouse pgk poly A |
| Chromosome |
10 |
| Common name |
No Data |
| Symbol description |
No Data |
|
Promoter |
mouse phosphoglycerate kinase promoter (PGK promoter) |
| 5 |
Symbol |
neo |
| Symbol name |
neomycin resistance gene (E. coli) |
| Chromosome |
10 |
| Common name |
neo; neomycin; |
| Symbol description |
No Data |
|
References |
No Data |
|
Research applications |
Cre/loxP system,
General Purpose,
Neurobiology Research |
|
Specific Term and Conditions |
The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. The DEPOSITOR should be a co-auther in articles when the users publish their data using these mice for 2 year after provided to the RIKEN BRC. Users should contact the DEPOSITOR in the case of application for any patents with the results from these mice. |
|
Additional information |
|
1 |
Lab HP (Japanese) |
|
2 |
Genotyping protocol <PCR> |
|
Depositor |
Sakimura, Kenji (Niigata University)  |
|
Strain Status /
Availability
(Expected delivery) |
|
