Strain Data Sheet
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Data update: Feb 21, 2014
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RBRC No. RBRC02351  
Type Targeted MutationCartagena  
Species Mus musculus  
Strain name C57BL/6-Slc1a3<tm1(cre)Ksak>  
Former Common name GLAST-Cre  
H-2 Haplotype No Data  
Background strain C57BL/6  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Mika Tsujita, Rie Natsume and Kenji Sakimura, Brain Research Institute, Niigata University in 2004. RENKA ES cells derived from C57BL/6NCrj were used. C57BL/6N background.  
Strain description Slc1a3 Cre knock-in mice. A Cre sequence was integrated into the start methionine site of the Slc1a3 (GLAST) gene at an in-frame position. A non-coding and pgk-neo cassette sequence are located downstream from Cre. The pgk-neo cassette can be removed, as it has an frt sequence on both sides.  
Colony maintenance Heterozygote x Wild-type [C57BL/6NCrlCrlj]  
Health Certificate No Data  
Gene Details
Promoter No Data  
 1 Symbol Slc1a3  
Symbol name Progesterone receptor  
Chromosome 15  
Common name B430115D02Rik, Eaat1, GLAST, Gmt1, MGluT1  
Symbol description No Data  
 2 Symbol cre  
Symbol name Phage P1 Cre recombinase  
Chromosome 15  
Common name No Data  
Symbol description No Data  
 3 Symbol frt  
Symbol name yeast FRT (flippase recombination target) sites  
Chromosome 15  
Common name No Data  
Symbol description No Data  
 4 Symbol poly A  
Symbol name mouse pgk poly A  
Chromosome 15  
Common name No Data  
Symbol description No Data  
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)  
 5 Symbol neo  
Symbol name neomycin resistance gene (E. coli)  
Chromosome 15  
Common name neo; neomycin;  
Symbol description No Data  
References No Data  
Research applications Cre/loxP system  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. The DEPOSITOR should be a co-auther in articles when the users publish their data using these mice for 2 year after provided to the RIKEN BRC. Users should contact the DEPOSITOR in the case of application for any patents with the results from these mice.  
Additional information
 1 Lab HP (Japanese)  
 2 Genotyping protocol <PCR>  
Depositor Sakimura, Kenji (Niigata University)  Sakimura, Kenji 
Strain Status /
Availability
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