Strain Information | |
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Image | |
BRC No. | RBRC02479 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6;129S-Hras1<tm1Mok> Grin2a<tm1Nak> Drd1a<tm1Mok> Drd5<tm1Mok> |
Former Common name | B6-Hras/NR2A/D1R/D5R KO |
H-2 Haplotype | |
ES Cell line | CCE/EK.CCE [129S/SvEv-Gpi1<c>] |
Background strain | |
Appearance | |
Strain development | Developed by Motoya Katsuki, National Institutes of Natural Sciences. |
Strain description | Hras, NR2A (Grin2a), D1R (Drd1a) and D5R (Drd5) genes multiple knockout mice. |
Colony maintenance | |
References | J. Neurosci., 16, 7859-7867 (1996). 8987814 J. Neurosci., 28(50):13390-13400 (2008). 19074012 PLoS One, 8(10):e75975 (2013). 24155877 Oncogene, 19, 2951-2956 (2000). 10871846 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter EcogptE.coli xanthine phosphoribosyltransferase13Ecogptmouse phosphoglycerate kinase promoter (PGK promoter) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)13neo; neomycin;herpes simplex virus thymidine kinase promoter (HSV tk promoter) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Grin2aglutamate receptor, ionotropic, NMDA2A (epsilon 1)16Grin2a<tm1Nak>targeted mutation 1, Shigetada Nakanishi Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)16neo; neomycin;herpes simplex virus thymidine kinase promoter (HSV tk promoter) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter EcogptE.coli xanthine phosphoribosyltransferase5Ecogptmouse phosphoglycerate kinase promoter (PGK promoter) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)5neo; neomycin;herpes simplex virus thymidine kinase promoter (HSV tk promoter) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter HrasHarvey rat sarcoma virus oncogene7Hras<tm1Mok>targeted mutation 1, Motoya Katsukic-H-ras, c-rasHa, H-ras, Ha-ras, Harvey-ras, Hras-1, ras Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)7 |
Ordering Information | |
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Donor DNA | herpes simplex virus thymidine kinase promoter (HSV tk promoter), E coli neo, mouse NMDAR2A genomic DNA, mouse Hras genomic DNA, mouse Drd1a genomic DNA, mouse Drd5 genomic DNA, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli xanthine phosphoribosyltransferase(Ecogpt) |
Research application | |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Oncogene, 19, 2951-2956 (2000). J. Neurosci., 16, 7859-7867 (1996). J. Neurosci., 28, 13390-13400 (2008).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Toshikuni Sasaoka (Niigata University) |
Strain Status | Frozen embryos |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |