Strain Data Sheet

RBRC02484

Strain Information

Image
BRC No.RBRC02484
TypeTargeted Mutation and TransgeneCartagena
SpeciesMus musculus
Strain nameB6.Cg-B6.Cg-Hras1<tm1Mok> Nras<tm1Mok> Tg(HRAS/floxed)1Mok
Former Common nameH-ras, N-ras double KO, L-Tg, B6-Hras KO/Nras KO/HRASfloxed Tg
H-2 Haplotype
ES Cell lineCCE/EK.CCE [129S/SvEv-Gpi1<c>]
Background strain
Appearance
Strain developmentDeveloped by Motoya Katsuki, National Institutes of Natural Sciences.
Strain descriptionHras knockout, Nras knockout and Lras transgenic triple mutant mice.
Colony maintenance
ReferencesOncogene. 2000 19(26):2951-6. 10871846
EMBO J. 21(5):1021-30 (2002). 11867530

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Csde1cold shock domain containing E1, RNA binding3Csde1

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Nrasneuroblastoma ras oncogene3Nras<tm1Mok>targeted mutation 1, Motoya KatsukiN-ras

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)3neo; neomycin;herpes simplex virus thymidine kinase promoter (HSV tk promoter)

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
HrasHarvey rat sarcoma virus oncogene7Hras<tm1Mok>targeted mutation 1, Motoya Katsukic-H-ras, c-rasHa, H-ras, Ha-ras, Harvey-ras, Hras-1, ras

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)7

Ordering Information

Donor DNAE. coli neo, mouse N-ras genomic DNA, mouse H-ras genomic DNA, human H-ras genomic DNA
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Oncogene, 19, 2951-2956 (2000). EMBO J., 21, 1021-1030 (2000).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorToshikuni Sasaoka (Niigata University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data