Strain Information | |
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Image | |
BRC No. | RBRC02522 |
Type | Targeted Mutation Congenic |
Species | Mus musculus |
Strain name | B6.Cg-Drd1a<tm1Mok> Drd1a<tm1(tTA)Mok> Tg(TRE-Drd1a/lacZ)1Mok |
Former Common name | D1TET, LacZD1R KO, B6-D1R KO D1R/tTA TRE-D1R/lacZ |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Motoya Katsuki, National Institutes of Natural Sciences. |
Strain description | D1R (Drd1a) knockout, D1R-tTA knock-in and TRE-D1R/lacZ transgene triple mutant mice. |
Colony maintenance | |
References | Front Cell Dev Biol., 3:38 (2015). 26137459 J. Neurosci., 28(50):13390-13400 (2008). 19074012 Cerebral Cortex., 25(12):4885-4897 (2015). 26443442 Front Integr Neurosci., 8:56 (2014). 25076876 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)13neo; neomycin;mouse phosphoglycerate kinase promoter (PGK promoter) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter tTAtTA (E. coli tet repressor (TetR), herpes simplex virus (HSV) VP16 activation domain)13tTAE. coli tet repressor (TetR), herpes simplex virus (HSV)VP16 activation domain Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Drd1dopamine receptor D1AUNDrd1C030036C15Rik, D1 receptor, Drd-1, Drd1, Gpcr15E. coli TRE promoter (tetracycline responsive promoter) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter lacZbeta-galactosidase (E. coli)UN |
Ordering Information | |
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Donor DNA | mouse Dopamine receptor 1 genomic DNA, E. coli neo, E. coli xanthine phosphoribosyltransferase (Ecogpt)tTA (E. coli tet repressor (TetR), herpes simplex virus (HSV) VP16 activation domain), E. coli tetracycline operator, E. coli lacZ |
Research application | Fluorescent Proteins/lacZ System Tet system |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Cerebral Cortex., 25, 4885-4897 (2015).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki and Dr. Toshikuni Sasaoka is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Toshikuni Sasaoka (Niigata University) |
Strain Status | Frozen embryos |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |