Strain Information | |
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Image | |
BRC No. | RBRC03899 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | STOCK Ephb1<tm1Cmn> Ephb2<tm1Paw> Ephb3<tm1Kln> EphB6<tm2Tom> |
Former Common name | EphB1, EphB2, EphB3, EphB6 fourfold knockout mice |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Toshimitsu Mastui, Kobe University Graduate School of Medicine. 129 and ICR mixed background.EphB1, EphB2, EphB3 KO: Mark Henkemeyer, University of Texas Southwestern Medical Center; EphB6 KO: Hiroshi Suzuki and Toshimitsu Mastui, Kobe University. |
Strain description | |
Colony maintenance | |
References | Biochem. Biophys. Res. Commun., 298, 87-94 (2002). 12379224 EMBO J., 15, 6035-6049 (1996). 8947026 J. Cell. Biol., 163, 1313-1326 (2003). 14691139 Eur. J. Immunol., 42, 1562-1572 (2012). 22622783 Cell, 86, 35-46, (1996). 8689685 Neuron., 39, 919-935 (2003). 12971893 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)16neo; neomycin;mouse phosphoglycerate kinase promoter (PGK promoter) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)4neo; neomycin;mouse phosphoglycerate kinase promoter (PGK promoter) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP6loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP6loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)6neo; neomycin;mouse phosphoglycerate kinase promoter (PGK promoter) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)9neo; neomycin; |
Ordering Information | |
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Donor DNA | mouse Phosphoglycerate kinase (PGK) promoter, E. coli neo, Phage P1 loxP sites, mouse Ephb1 genomic DNA, mouse Ephb2 genomic DNA, mouse Ephb3 genomic DNA, mouse Ephb6 genomic DNA |
Research application | Cell Biology Research Cre/loxP system Neurobiology Research |
Specific Term and Conditions | 1. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literatures designated by use of the DEPOSITOR is requested. Henkemeyer et al., 1996 paper in Cell for EphB2/EphB3, Williams et al., 2003 paper in Neuron for EphB1. Shimoyama et al., 2002 paper in BBRC for EphB6, or Kawano et. al., 2012 paper in Eur. J. Immunol. for EphB1/EphB2/EphB3/EphB6 quadruple mutant mice. 2. UT Southwestern would like to limit the use of the BIOLOGICAL RESOURCE to non-profit institutions, also limit the use to academic research purposes and for-profit institutions or use for commercial research purposes shall acquire a prior written consent from the Depositor, a recipient shall acquire a prior written consent form the Depositor prior to filing an application for a patent, or intellectual property or other right based on the results research using the BIOLOGICAL RESOURCE. |
Depositor | Drs. Toshimitsu Matsui and Mark Henkemeyer (Kobe University/ University of Texas Southwestern Medical Center) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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