Strain Information | |
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Image | |
BRC No. | RBRC04696 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6;B6CB-Agtr1a<tm1Afu> |
Former Common name | B6-AT1a KO |
H-2 Haplotype | |
ES Cell line | TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1] |
Background strain | |
Appearance | |
Strain development | Developed by Akiyoshi Fukamizu, Institute of Applied Biochemistry, Tsukuba Advanced Researrch Alliance, University of Tukuba in 1995. |
Strain description | |
Colony maintenance | |
References | J. Biol. Chem., 270, 18719-18722 (1995). 7642517 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter lacZbeta-galactosidase (E. coli)13 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)13herpes simplex virus thymidine kinase promoter (HSV tk promoter) |
Ordering Information | |
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Donor DNA | Mouse AT1a genomic DNA, E. coli neo<r>, E. coli lacZ, herpes simplex virus thymidine kinase promoter (HSV tk promoter)[update Feb 12, 2014] |
Research application | Cell Biology Research Fluorescent Proteins/lacZ System Mouse Models for Human Disease |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Biol. Chem., 270, 18719-18722 (1995).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. |
Depositor | Akiyoshi Fukamizu (University of Tsukuba) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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Kawakami-Mori F, Nishimoto M, Reheman L, Kawarazaki W, Ayuzawa N, Ueda K, Hirohama D, Kohno D, Oba S, Shimosawa T, Marumo T, Fujita T. Aberrant DNA methylation of hypothalamic angiotensin receptor in prenatal programmed hypertension. JCI Insight 3(21) (2018) 30385711 |