Strain Information | |
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Image | |
BRC No. | RBRC04709 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | FVB.Cg-Atp2b2<tm1Ges> |
Former Common name | |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed Dr. Gary Shull, University of Cincinnati College of Medicine. Deposited by Dr. Thomas Knoepfel, RIKEN Brain Science Institute. |
Strain description | PMCA2 knockout mouse. Deficient in the plasma membrane Ca2+ ATPase variant 2, PMCA2. Homozygous mutant mice are viable but show motor deficits, deficits in hearing and disturbance of the sense of balance. |
Colony maintenance | Heterozygote x Wild-type |
References | J. Biol. Chem., 273, 18693-18696 (1998). 9668038 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)6mouse phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
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Donor DNA | mouse PMCA2 genomic DNA, E. coli neomycin resistance gene, mouse phosphoglycerate kinase promoter (PGK promoter) |
Research application | |
Specific Term and Conditions | No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.) |
Depositor | Thomas Knöepfel (RIKEN) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |