Strain Information | |
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Image | |
BRC No. | RBRC04753 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6;129S4(Cg)-Socs1<tm1Ayos> |
Former Common name | Socs1 floxed |
H-2 Haplotype | |
ES Cell line | J1 [129S4/SvJae] |
Background strain | |
Appearance | |
Strain development | Developed by Akihiko Yoshimura, Medical Institute of Bioregulation, Kyushu University. |
Strain description | Scocs1 floxed mice. A loxP site was inserted downstream of exon 1 and an additional loxP site was inserted in exon 2. |
Colony maintenance | Heterozygote x Wild-type [C57BL/6JJcl] Homozygous mice are viable and fertile. |
References | J. Immunol., 180, 3746-3756 (2008). 18322180 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Socs1suppressor of cytokine signaling 116Socs1<tm1Ayos>targeted mutation 1, Akihiko YoshimuraCish1, Cish7, JAB, JAK-binding protein, JAK2-binding protein, SOCS-1, SSI-1, STAT-induced STAT inhibitor 1 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP16loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP16loxP |
Ordering Information | |
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Donor DNA | Phage P1 loxP sites, Mouse Socs1 genomic DNA |
Research application | Cre/loxP system Immunology and Inflammation Research |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Immunol., 180, 3746-3756 (2008). In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. |
Depositor | Akihiko Yoshimura (Keio University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |