Strain Data Sheet

RBRC04859

Strain Information

Image
BRC No.RBRC04859
TypeSpontaneous Mutation
SpeciesMus musculus
Strain nameB10.BR-Tyrp1<b>/Hir
Former Common nameB10-b
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Tomohisa Hirobe, National Institute of Radiological Sciences in 1986. Brown (b) locus from C57BR/cdJMs was backcrossed into the C57BL/10JMsHir, and then mantained by sister-brother mating.
Strain descriptionC57BL/10 congenic strain of brwon locus from C57BR strain. Brown (a/a b/b C/C D/D P/P E/E). Low number of melanocytes.
Colony maintenanceHomozygote x Homozygote
ReferencesPigment Cell Res., 12, 147-163 (1992). 10385911
Histol Histopathol., 10, 223-237 (1995). 7756740
Pigment Cell Res., 18, 2-12 (2005). 15649147
Pigment Cell Melanoma Res., 24(3):462-478 (2011). 21375698
Pigment Cell Res., 5, 1-11 (1992). 1631016

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Tyrp1tyrosinase-related protein 14Tyrp1<b>brown

Ordering Information

Donor DNA
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Pigmnet Cell Melanoma Res., 24(3):462-478 (2011). In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
DepositorTomohisa Hirobe (National Institute of Radiological Sciences (NIRS))
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved embryos (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data