Strain Information | |
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Image | |
BRC No. | RBRC04901 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6D2;129(Cg)-Sox2<tm2.1Knd> |
Former Common name | Sox2 enhancer N2 KO |
H-2 Haplotype | |
ES Cell line | R1 [(129X1/SvJ x 129S1/Sv)F1-Kitl<+>] |
Background strain | Slc:B6D2F1 |
Appearance | |
Strain development | Developed by Hisato Kondoh, Graduate School of Frontier Biosciences, Osaka University in 2007. An enhancer N2 was replaced with floxed neocassette. Cre-mediated recombination by corossing with CAGGS-Cre mice removed the neo cassete. The mice were crossed to B6D2F1. |
Strain description | |
Colony maintenance | Homozygote x Heterozygote [or Crossing to Slc:B6D2F1] Homozygous mutant mice are viable and fertile. |
References | Dev. Biol., 352, 354-366 (2011). 21185279 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP3loxP |
Ordering Information | |
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Donor DNA | Bacteriophage P1 Flox 配列 |
Research application | Cre/loxP system |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Developmental Biology, 352, 354-366 (2011). |
Depositor | Hisato Kondoh (Osaka University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |