Strain Data Sheet

RBRC04911

Strain Information

Image
BRC No.RBRC04911
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129P2-Mc2r<tm1Dchi>
Former Common nameB6.129P2-Mc2r<tm1Dchi>
H-2 Haplotype
ES Cell lineE14 [129P2/OlaHsd]
Background strain
Appearance
Strain developmentDeveloped by Yoichiro Iwakura, The Institute of Medical Science, The University of Tokyo and Mitsumasa Kubo, Hokkaido University of Education in 2007. The mice were backcrossed to C57BL/6 for at least 5 times.
Strain descriptionMC2R knockout mice. Most of homozygous mutant mice were perinatal lethal.
Colony maintenance
ReferencesProc. Natl. Acad. Sci. USA, 104, 18205-18210 (2007). 17989225

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Mc2rmelanocortin 2 receptor18Mc2r<tm1Dchi>targeted mutation 1, Dai Chida

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)18neo; neomycin;mouse phosphoglycerate kinase promoter (PGK promoter)

Ordering Information

Donor DNAmouse Phosphoglycerate kinase (PGK) promoter, E. coli Neomycin resistance gene, mouse Mc2r genomic DNA
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Proc. Natl. Acad. Sci. U S A.,104, 18205-18210 (2007). Please obtain the written consent from Professor Yoichiro Iwakura (iwakura@rs.tus.ac.jp; Research Institute for Biological Sciences, Tokyo University of Science) for the use.
DepositorYoichiro Iwakura (The University of Tokyo)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data