Strain Data Sheet

RBRC05132

Strain Information

Image
BRC No.RBRC05132
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameC3H/HeN-Tg(CD4-HTLVtax)5562Yiw
Former Common nameC3H/HeN-Tg(CD4-HTLVtax)5562Yiw
H-2 Haplotype
ES Cell line
Background strainC3H/HeNSlc
Appearance
Strain developmentDeveloped by Yoichiro Iwakura, The Institute of Medical Science, The University of Tokyo in 1999. Transgene was injected into the pronuclei of C3H/HeN fertilized eggs.
Strain descriptionTransgenic mice having tax region of human T cell leukemia virus type-I (HTLV-I) (transgene expresses in T cells). Tg mice develop chronic arthritis resembling rheumatoid arthritis, and also show a Sjögren syndrome-like autoimmune disorder. C3H background.
Colony maintenance
ReferencesJ. Immunol.,62, 2956-2963 (1999). 10072546

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
tax (HTLV-I)tax (HTLV-I)UNtax (HTLV-I)mouse Cd4 promoter

Ordering Information

Donor DNACD4 promoter (mouse), human T cell leukemia virus type-I (HTLV-I) tax
Research applicationImmunology and Inflammation Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Immunol., 62, 2956-2963 (1999).Please obtain the written consent from Professor Yoichiro Iwakura (iwakura@rs.tus.ac.jp; Research Institute for Biological Sciences, Tokyo University of Science) for the use.
DepositorYoichiro Iwakura (The University of Tokyo)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data