Strain Information | |
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Image | |
BRC No. | RBRC05132 |
Type | Transgene |
Species | Mus musculus |
Strain name | C3H/HeN-Tg(CD4-HTLVtax)5562Yiw |
Former Common name | C3H/HeN-Tg(CD4-HTLVtax)5562Yiw |
H-2 Haplotype | |
ES Cell line | |
Background strain | C3H/HeNSlc |
Appearance | |
Strain development | Developed by Yoichiro Iwakura, The Institute of Medical Science, The University of Tokyo in 1999. Transgene was injected into the pronuclei of C3H/HeN fertilized eggs. |
Strain description | Transgenic mice having tax region of human T cell leukemia virus type-I (HTLV-I) (transgene expresses in T cells). Tg mice develop chronic arthritis resembling rheumatoid arthritis, and also show a Sjögren syndrome-like autoimmune disorder. C3H background. |
Colony maintenance | |
References | J. Immunol.,62, 2956-2963 (1999). 10072546 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter tax (HTLV-I)tax (HTLV-I)UNtax (HTLV-I)mouse Cd4 promoter |
Ordering Information | |
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Donor DNA | CD4 promoter (mouse), human T cell leukemia virus type-I (HTLV-I) tax |
Research application | Immunology and Inflammation Research |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Immunol., 62, 2956-2963 (1999).Please obtain the written consent from Professor Yoichiro Iwakura (iwakura@rs.tus.ac.jp; Research Institute for Biological Sciences, Tokyo University of Science) for the use. |
Depositor | Yoichiro Iwakura (The University of Tokyo) |
Strain Status | Frozen embryos |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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