Strain Information | |
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Image | |
BRC No. | RBRC05283 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.Cg-Noto<tm1(cre/ERT2)Hssk>/Rbrc |
Former Common name | Noto(nmCherry-CreERT2) (Acc. No. CDB0579K) |
H-2 Haplotype | |
ES Cell line | TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1] |
Background strain | |
Appearance | |
Strain development | Developed by Hiroshi Sasaki, RIKEN Center for Developmental Biology. |
Strain description | mCherry-creER2 Noto knockin mice. About 50% of homozygotes display varying degrees of tail defects. |
Colony maintenance | Heterozygote x Wild-type [C57BL/6N] About 50% of homozygotes display varying degrees of tail defects. |
References | Mech. Dev., 126, 791-803 (2009). 19720144 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter E2AEquine rhinitis A virus (ERAV) 2A peptide6E2A Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter ERT2estrogen receptor (ER), human ER with the triple mutation G400V/M543A/L544A)6ERT2 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter H2Bhuman Histone H2B cDNA6H2B Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter T2AThosea asigna virus 2A peptide (insect)6T2A Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter crePhage P1 Cre recombinase6cre Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP6loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter mCherryRed Fluorescent Protein (Discosoma sp.)6mCherry |
Ordering Information | |
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Donor DNA | E2A [equine rhinitis A virus 2A peptide], human histone H2B cDNA,Discosoma sp. mCherry cDNA, T2A [Thosea asigna virus 2A peptide], Phage P1 Cre recombinase DNA, human Estrogen receptor cDNA, Phage P1 loxP site, mouse Noto genomic DNA |
Research application | Cre/loxP system Fluorescent Proteins/lacZ System |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Acc.No. CDB0579K and Web. Site (https://large.riken.jp/distribution/mutant-list.html) is requested. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (Mech Dev. 2009 126(10):791-803.) Please inform the DEPOSITOR (mutant.bdr@riken.jp) about the paper when published. |
Depositor | RIKEN CDB (RIKEN CDB) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |