Strain Information | |
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Image | |
BRC No. | RBRC05387 |
Type | Transgene |
Species | Mus musculus |
Strain name | B6;B6C3(129)-Tg(NDE-hsp-Pkd2*D509V/Venus)1Hmd |
Former Common name | B6-NDE-Pkd2m2-venus Tg#1 |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Dr. Satoko Yoshiba and Dr. Hiroshi Hamada, Graduate School of Frontier Biosciences, Osaka University in 2010. The transgene was microinjected into the pronuclei of B6C3F1 fertilized eggs. |
Strain description | This transgenic mouse expresses the D509V variant Pkd2 and venus fusion gene on both sides of the node, node under the control of the mouse node-specific enhancer. |
Colony maintenance | Carrier x Noncarrier [C57BL/6JJcl] |
References | Science, 338, 226-231 (2012). 22983710 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Pkd2polycystic kidney disease 2UNPkd2mouse Nodal node-notochord enhancer, mouse Hsp68 promoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter VenusYellow Fluorescent Protein (Aequorea victoria)UNVenus |
Ordering Information | |
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Donor DNA | Mouse Pkd2 gene cDNA, SV40 polyA signal, Aequorea victoria Venus (改良型GFP), Mouse Nodal node-notochord enhancer, Mouse Hsp68 promoter |
Research application | Fluorescent Proteins/lacZ System |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Science, 338, 226-231 (2012).In publishing the research results obtained by use of the BIOLOGICAL RESOURCE containing Venus, an acknowledgment to Dr. Atsushi Miyawaki and a citation of the following literature(s) designated by the DEPOSITOR are requested. Nat. Biotechnol., 20, 87-90 (2002). |
Depositor | Hiroshi Hamada (RIKEN CDB) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |