Strain Information | |
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Image | |
BRC No. | RBRC05507 |
Type | Transgene |
Species | Mus musculus |
Strain name | D1.Cg-Tg(Col2-Cd80)1 |
Former Common name | D1BC, D1-C2-Cd80 Tg |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Satoshi Kanazawa, Nagoya City University Graduate School of Medical Sciences. DBA/1J background. |
Strain description | Transgenic mice having a mouse B7.1 (Cd80) under the control of the rat Col2 promoter and enhancer. Tg mice develop chronic progressive arthritis by inoculation of low dose of CII. |
Colony maintenance | Homozygote x Homozygote [or Crossing to DBA/1JNCrlj] |
References | Proc. Natl. Acad. Sci. USA, 103, 14465-14470 (2006). 16980409 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter AmpAmpicillin resistance gene (E. coli)UNAmp Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Cd80CD80 antigenUNCd80rat Type II collagene promoter and enhancer Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter SV40 Poly A signalUN |
Ordering Information | |
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Donor DNA | E.coli Ampcilin registant gene, mouse B7.1 gene cDNA, rat Type II collagene promoter and enhancer, SV40 Poly A signal |
Research application | |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Proc. Natl. Acad. Sci. U S A., 103, 14465-14470 (2006). |
Depositor | Satoshi Kanazawa (Nagoya City University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |