Strain Information | |
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Image | |
BRC No. | RBRC05512 |
Type | Inbred |
Species | Mus musculus |
Strain name | C57BL/10ScCr |
Former Common name | B10ScCr |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Maintained by Gris Galanos, Max-Planck-Institute for Immunobiology |
Strain description | This strain is homozygous for the defective lipopolysaccharide and IL-12 interferon responses (Tlr4<lps-del> and Il12rb2<Ifnm-d>). |
Colony maintenance | Tlr4 : Homozygote x Homozygote ; Il12rb2 : Homozygote x Homozygote Homozygous mutant mice are viable and fertile. |
References | J. Immunol., 167, 2106-2111 (2001). 11489994 Science, 282, 2085-2088 (1998). 9851930 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Il12rb2interleukin 12 receptor, beta 26Il12rb2<Ifnm-d>interferon response to microorgansisms, defective |
Ordering Information | |
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Donor DNA | |
Research application | Immunology and Inflammation Research |
Specific Term and Conditions | No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.) |
Depositor | Hiroaki Takimoto (Kitasato University) |
Strain Status | Frozen embryos |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |