Strain Information | |
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Image | |
BRC No. | RBRC05542 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | C57BL/6-Puf60<tm1>/CU |
Former Common name | FIR floxed, B6-Puf60 floxed |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Kazuyuki Matsushita, Atsushi Iwama and Fumio Nomura, Graduate School of Medicine, Chiba University. C57BL/6 background (C57BL/6JJcl and C57BL/6NCrlCrlj mixed). |
Strain description | FIR, RBP Interacting repressor (Puf60) floxed mice. A loxP site was inserted upstream of exon 3, and a PGK-neo cassette and loxP site were inserted down stream of exon 5. Conditional FIR deficient mice can be generated by crossing with tissue-specific Cre mice. |
Colony maintenance | Heterozygote x Wild-type [C57BL/6NCrlCrlj] |
References | Cancer Res., 66, 1409-1417 (2006). 16452196 Oncotarget, 6(7):5102-17 (2015). 25671302 Cancer Sci., 104, :149-156 (2013). 23113893 Mol. Cancer Res., ;11, 689-698 (2013). 23594796 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter |
Ordering Information | |
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Donor DNA | Mouse FBP Interacting repressor genomic DNA, Mouse PGK promoter, E. coli Neomycin resistance gene, Phage P1 loxP |
Research application | |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Oncotarget, 6(7):5102-17 (2015). |
Depositor | Fumio Nomura (Chiba University) |
Strain Status | Frozen embryos |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |