Strain Data Sheet

RBRC05542

Strain Information

Image
BRC No.RBRC05542
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6-Puf60<tm1>/CU
Former Common nameFIR floxed, B6-Puf60 floxed
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Kazuyuki Matsushita, Atsushi Iwama and Fumio Nomura, Graduate School of Medicine, Chiba University. C57BL/6 background (C57BL/6JJcl and C57BL/6NCrlCrlj mixed).
Strain descriptionFIR, RBP Interacting repressor (Puf60) floxed mice. A loxP site was inserted upstream of exon 3, and a PGK-neo cassette and loxP site were inserted down stream of exon 5. Conditional FIR deficient mice can be generated by crossing with tissue-specific Cre mice.
Colony maintenanceHeterozygote x Wild-type [C57BL/6NCrlCrlj]
ReferencesCancer Res., 66, 1409-1417 (2006). 16452196
Oncotarget, 6(7):5102-17 (2015). 25671302
Cancer Sci., 104, :149-156 (2013). 23113893
Mol. Cancer Res., ;11, 689-698 (2013). 23594796

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Puf60poly-U binding splicing factor 6015Puf60

Ordering Information

Donor DNAMouse FBP Interacting repressor genomic DNA, Mouse PGK promoter, E. coli Neomycin resistance gene, Phage P1 loxP
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Oncotarget, 6(7):5102-17 (2015).
DepositorFumio Nomura (Chiba University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data