Strain Information | |
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Image | |
BRC No. | RBRC05559 |
Type | Transgene |
Species | Mus musculus |
Strain name | B6.Cg-Tg(Crx-cre/ERT2)1Tfur |
Former Common name | 129S6;B6C3-Tg(Crx-cre/ERT2)1Tfur, 129-CrxCreERT2, 129-CrxCreER Tg |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Takahisa Furukawa, Osaka Bioscience Institute in 2008. The transgene was injected into the pronuclei of B6C3F1 fertilized eggs. |
Strain description | Crx-creERT2 transgenic mice. This transgenic mouse expresses tamoxifen-inducible cre recombinase gene in retinal photoreceptor cells and progenitor cells under the control of the mouse Crx promoter. |
Colony maintenance | Carrier x Noncarrier [C57BL/6NCrlCrlj] |
References | J. Neurosci., 31, 16792-16807 (2011). 22090505 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter ERT2estrogen receptor (ER), human ER with the triple mutation G400V/M543A/L544A)UNERT2 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter SV40 polyA signalUN |
Ordering Information | |
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Donor DNA | mouse Crx promoter, phage P1 Cre recombinase gene, SV40 polyA signal, human Estrogen receptor binding domain (ERT2) |
Research application | Cre/loxP system |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Neurosci., 31, 16792-16807 (2011).Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must contract an MTA with the DEPOSITOR (Osaka University). |
Depositor | Takahisa Furukawa (Osaka Bioscience Institute) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- Mouse of the Month May 2013 |
BRC mice in Publications |
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No Data |