Strain Information | |
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Image | |
BRC No. | RBRC05650 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6;129S-Zrsr1<tm1Mok> |
Former Common name | UNG, B6;129S-Zrsr1<tm1Mok>, u2af1-rs1 KO |
H-2 Haplotype | |
ES Cell line | CCE/EK.CCE [129S/SvEv-Gpi1<c>] |
Background strain | |
Appearance | |
Strain development | Developed by Motoya Katsuki, National Institutes of Natural Sciences (Institute of Medical Science, University of Tokyo). |
Strain description | u2af1-rs1 (Zrsr1) gene knockout mice. The entire coding region and about 3/4 of the CpG islands including region II were replaced with a PGK-gpt-neo cassette. |
Colony maintenance | Heterozygote x Wild-type [C57BL/6JJcl] |
References | Biochem. Biophys. Res. Commun., 268, 590-595 (2000). 10679248 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Zrsr1zinc finger (CCCH type), RNA binding motif and serine/arginine rich 111Zrsr1<tm1Mok>targeted mutation 1, Motoya Katsuki Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)11neo; neomycin;herpes simplex virus thymidine kinase promoter (HSV tk promoter) |
Ordering Information | |
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Donor DNA | herpes simplex virus thymidine kinase promoter (HSV tk promoter), E. coli xanthine phosphoribosyltransferase (Ecogpt), E. coli neomycin resistance gene, mouse u2af1-rs1 genomic DNA |
Research application | |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Biochem. Biophys. Res. Commun., 268, 590-595 (2000).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Toshikuni Sasaoka (Niigata University) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |