Strain Information | |
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Image | |
BRC No. | RBRC05844 |
Type | Transgene |
Species | Mus musculus |
Strain name | C57BL/6-Tg(Pmch-tTA)BAhky |
Former Common name | MCH-tTA, B6-MCH-tTA Tg, C57BL/6-Tg(MCH-tTA)1Ahky |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6JJcl |
Appearance | |
Strain development | Dr. Akihiro Yamanaka, National Institute for Physiological Sciences in 2010. C57BL/6J background. MCH locus of the BAC RP23-348H6 clone was replaced with tTA. |
Strain description | Melanin-concentrating hormone (MCH) neuron specific tTA BAC transgenic mice. |
Colony maintenance | Carrier x Noncarrier [C57BL/6JJcl]Tg mice are viable and fertile. |
References | J. Neurosci., 34(20):6896-909 (2014). 24828644 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter tTAtTA (E. coli tet repressor (TetR), herpes simplex virus (HSV) VP16 activation domain)UNtTAE. coli tet repressor (TetR), herpes simplex virus (HSV)VP16 activation domainmouse melanin-concentrating hormone (MCH) promoter |
Ordering Information | |
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Donor DNA | mouse melanin-concentrating hormone (MCH) genomic DNA (mouse BAC PR23-348H6), tTA (E. coli tet repressor (TetR), herpes simplex virus (HSV) VP16 activation domain), SV40 polyA, Phage P1 loxP site from BAC vector |
Research application | Neurobiology Research Tet system |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Akihiro Yamanaka (Nagoya University) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |