Strain Information | |
---|---|
Image | |
BRC No. | RBRC06025 |
Type | Transgene |
Species | Mus musculus |
Strain name | ICR-Tg(Hes5-Ub-NLS-luc2)1Imayo |
Former Common name | pHes5-NLS-Ub-luc2 ; Hes5-Ub/NLS/luc2 Tg#1 |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Itaru Imayoshi and Ryoichiro Kageyama, Institute for Virus Research, Kyoto University in 2011. The transgene was injected into the pronuclei of ICR fertilized eggs. |
Strain description | Hes5 luc trasngenic mice. Nuclear-localized destabilized luciferase (Ub-NLS-luc2) is expressed under the control of Hes5 promoter. |
Colony maintenance | Carrier x Noncarrier [or Crossing to Slc:ICR] |
References | Science, 342(6163):1203-8. doi: 10.1126/science.1242366. 24179156 |
Health Report | |
---|---|
Examination Date / Room / Rack |
Gene | |
---|---|
Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter UBmutant ubiquitin (G76V)UNUB Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter luc2Photinus pyralis LuciferaseUNluc2 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter nlsSV40 large T antigen nuclear localization signal (NLS)UNnls |
Ordering Information | |
---|---|
Donor DNA | mouse Hes5 promoter, human ubiquitin, four copies of nuclear-localization signal from SV40 largeT antigen, optimized firefly luciferase luc2 (synthetic) cDNA, Hes5 cDNA, Hes5 3' UTR |
Research application | |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Science DOI: 10.1126/science.1242366In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. The RECIPIENT of BIOLOGICAL resource shall obtain a prior written consent on use of it from the DEPOSITOR Dr. Itaru Imayoshi (E-mail: iimayosh@virus.kyoto-u.ac.jp) and Ryoichiro Kageyama (E-mail: rkageyam@virus.kyoto-u.ac.jp ). (No approval form (Form D) is necessary). |
Depositor | Drs. Ryoichiro Kageyama and Itaru Imayoshi (Kyoto University) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
---|
No Data |