Strain Information | |
---|---|
Image | |
BRC No. | RBRC06055 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.Cg-Mc4r<tm1.1Hko> |
Former Common name | MCR Delta lox/+ (GWAS023), B6-Mc4r KO |
H-2 Haplotype | |
ES Cell line | M1 [(C57BL/6 x 129)F1] |
Background strain | |
Appearance | |
Strain development | Developed by Haruhiko Koseki, RIKEN Center for Allergy and Immunology. M1 ES cells derived from (C57BL/6 x 129)F1 were used for the generation of knockout mice. Exon 1 and neo cassette were removed by crossing with CAG-Cre mice (C57BL/6 background). The mutant mice were crossed to C57BL/6J. |
Strain description | MCR4 (Mcr4) gene knockout mice. Exon 1 was removed. |
Colony maintenance | Heterozygote x Wild-type [C57BL/6JJcl] |
References |
Health Report | |
---|---|
Examination Date / Room / Rack | 2023/04/10Room:3-BRack:G 2023/01/10Room:3-BRack:G 2022/10/11Room:3-BRack:G 2022/07/11Room:3-BRack:G |
Gene | |
---|---|
Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP18loxP |
Ordering Information | |
---|---|
Donor DNA | phage P1 loxP site, mouse Mc4r genomic DNA |
Research application | Cre/loxP system |
Specific Term and Conditions | The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Haruhiko Koseki (RIKEN) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
---|
No Data |