Strain Information | |
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Image | |
BRC No. | RBRC06156 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | C57BL/6N-Slc5a4a<tm1Csk> |
Former Common name | SGLT3a knockout mouse, SGLT3a KO, B6-Slc5a4a KO |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6NCrlCrlj |
Appearance | |
Strain development | Developed by Chugai Pharmaceutical Co., Ltd. ES cells derived from C57BL/6N were used to disrupt the Slc5a4a gene by homologous recombination. C57BL/6N background. |
Strain description | Slc5a4a (SGLT3a) gene knockout mice. Exon 1 to 2 and part of exon 3 were replaced with a PGK neo cassette. Homozygous mutant mice show no obvious abnormality. |
Colony maintenance | Homozygote x Homozygote [or Crossing to C57BL/6NCrlCrlj] |
References |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Slc5a4asolute carrier family 5, member 4a10Slc5a4a<tm1Csk>targeted mutation 1, Chugai Pharmaceutical Co., Ltd. Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)10mouse Phosphoglycerate kinase promoter (PGK promoter), phage T7 gb2 promoter |
Ordering Information | |
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Donor DNA | mouse Phosphoglycerate kinase promoter (PGK promoter), phage T7 gb2 promoter (synthetic), E. coli Neomycine resistance gene, (synthetic) polyA signal, mouse Slc5a4a genomic DNA |
Research application | |
Specific Term and Conditions | The RECIPIENT of the BIOLOGICAL RESOURCE is requested to make a Material Transfer Agreement specified by the DEPOSITOR. (Contact info: Mr. Taku Fukuzawa <fukuzawatk@chugai-pharm.co.jp>, Discovery Pharmacology Dept.) |
Depositor | Kou-ichi Jishage (Chugai Pharmaceutical Co., Ltd.) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |