Strain Information | |
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Image | |
BRC No. | RBRC06158 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | C57BL/6N-Del(10Slc5a4a-Slc5a4b)Csk |
Former Common name | SGLT3a/3b double knockout mouse, SGLT3a/3b dKO, B6-10Slc5a4a/4b KO |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6NCrlCrlj |
Appearance | |
Strain development | Developed by Chugai Pharmaceutical Co., Ltd. ES cells derived from C57BL/6N were used. C57BL/6N background. |
Strain description | Slc5a4a (SGLT3a) and Slc5a4b (SGLT3b) genes double knockout mice. Exon 1 to 5 of the Slc5a4b and exon 1 to 2 and part of exon 3 of Slc5a4a were deleted. Homozygous mutant mice show no obvious abnormality. |
Colony maintenance | Heterozygote x Wild-Type [or Crossing to C57BL/6NCrl] |
References |
Health Report | |
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Examination Date / Room / Rack | 2024/01/09Room:3-BRack:J 2023/10/10Room:3-BRack:J 2023/07/10Room:3-BRack:J 2023/04/10Room:3-BRack:J 2023/01/10Room:3-BRack:J 2022/10/11Room:3-BRack:J 2022/07/11Room:3-BRack:J |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Slc5a4bsolute carrier family 5 (neutral amino acid transporters, system A), member 4b10Slc5a4bdeletion, Chr 10, Chugai Pharmaceutical Co., Ltd.deletion, Chr 10, Chugai Pharmaceutical Co., Ltd. Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Slc5a4asolute carrier family 5, member 4a10Slc5a4adeletion, Chr 10, Chugai Pharmaceutical Co., Ltd.deletion, Chr 10, Chugai Pharmaceutical Co., Ltd. Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP10loxP |
Ordering Information | |
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Donor DNA | phage P1 loxP site, mouse Slc5a4a genomic DNA, mouse Slc5a4b genomic DNA |
Research application | Cre/loxP system |
Specific Term and Conditions | The RECIPIENT of the BIOLOGICAL RESOURCE is requested to make a Material Transfer Agreement specified by the DEPOSITOR. (Contact info: Mr. Taku Fukuzawa <fukuzawatk@chugai-pharm.co.jp>, Discovery Pharmacology Dept.) |
Depositor | Kou-ichi Jishage (Chugai Pharmaceutical Co., Ltd.) |
Strain Status | Live mice Frozen embryos Frozen sperm |
Strain Availability | Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) Live mouse (1 to 3 months) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |