Strain Information | |
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Image | |
BRC No. | RBRC06217 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6;129-Slc39a13<tm1Thir> |
Former Common name | ZIP13 KO, B6-Slc39a13 KO |
H-2 Haplotype | |
ES Cell line | R1 [(129X1/SvJ x 129S1/Sv)F1-Kitl<+>] |
Background strain | |
Appearance | |
Strain development | Developed by Toshiyuki Fukuda, RIKEN Center for Allergy and Immunology in 2008. R1 ES cells derived from (129X1/SvJ x 129S1/Sv)F1-Kitl<+> were used for the generation of knockout mice. The mutant mice were crossed to C57BL/6J. |
Strain description | Zip13 (Slc39a13) gene knockout mice. Exons 6 through 8 were replaced with a neo cassette. |
Colony maintenance | Heterozygote x Wild-type [C57BL/6JJcl] |
References | PLoS Genet. 2017 Aug 30;13(8):e1006950. doi: 10.1371/journal.pgen.1006950. eCollection 2017 Aug. 28854265 PLoS One. 3(11):e3642 (2008). 18985159 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Slc39a13solute carrier family 39 (metal ion transporter), member 132Slc39a13<tm1Thir>targeted mutation 1, Toshio Hirano Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)2mouse phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
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Donor DNA | mouse phosphoglycerate kinase promoter (PGK promoter), E. coli Neomycin resistance gene, mouse Slc39a13 genomic DNA |
Research application | Dermatology Research Developmental Biology Research Mouse Models for Human Disease |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. PLoS One. 3(11):e3642 (2008).Prior to requesting the BIOLOGICAL RESOURCE, the Recipient shall contact with the Developer scientist (Dr. Toshiyuki Fukada, email: fukada@ph.bunri-u.ac.jp) and obtain the use permission. |
Depositor | Drs. Shigeo Koyasu and Toshiyuki Fukada (RIKEN) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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Hirose T, Shimazaki T, Takahashi N, Fukada T, Watanabe T, Tangkawattana P, Takehana K. Morphometric analysis of thoracic aorta in Slc39a13/Zip13-KO mice. Cell Tissue Res 376(1) 137-141(2019) 30610452 Hirose T, Suzuki I, Takahashi N, Fukada T, Tangkawattana P, Takehana K. Morphometric analysis of cornea in the Slc39a13/Zip13-knockout mice. J Vet Med Sci 80(5) 814-818(2018) 29563392 |