Strain Information | |
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Image | |
BRC No. | RBRC06318 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | BALB/c-Cables1<tm1Utr> |
Former Common name | BALB-Cables1 KO |
H-2 Haplotype | |
ES Cell line | |
Background strain | BALB/cAnNCrlCrlj |
Appearance | |
Strain development | Developed by Fumihiro Sugiyama, Laboratory animal resource center, University of Tsukuba in 2014. BALB/c derived ES cells were used to generate the knockout mice. |
Strain description | Cables1 gene null knockout mice. Exon 1 was replaced with a neo cassette. Homozygous mutant mice show no obvious abnormality. |
Colony maintenance | Homozygote x Homozygote [or Crossing to BALB/cAnNCrlCrlj] |
References | Laboratory Investigation, 94, 321-330 (2014) . 24336072 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site18Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site18Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP18loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP18loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)18human phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
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Donor DNA | Mouse Cables1 genomic DNA, human phosphoglycerate kinase promoter (PGK promoter), E. coli Neomycin resistance gene, phage P1 loxP, yeast FRT sites |
Research application | Cre/loxP system Developmental Biology Research FLP/frt system |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Truncated Cables1 Causes agenesis of the corpus callosum in mice. |
Depositor | Fumihiro Sugiyama (University of Tsukuba) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |