Strain Data Sheet
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Data update: Oct 24, 2017
Health Report   PCR Protocol   Thawing Method
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RBRC No. RBRC06410  
Type Targeted MutationCartagena  
Species No Data  
Strain name B6.Cg-Nfkbiz<tm1.1Muta>  
Former Common name IκB-ζ flox/flox, B6-Nfkbiz floxed  
H-2 Haplotype No Data  
ES cell line Bruce 4 [B6.Cg-Thy1]  
Background strain No Data  
Appearance
 1 Appearance No Data  
Genotype No Data  
Strain development Developed by Tatsushi Muta, Graduate School of Life Sciences, Tohoku University. Bruce 4 ES cells were used to generate the mutant mice. A frt-neo cassette was removed by crossing with CAG-FLPe (B6) mice.  
Strain description Nfkbiz gene floxed mice. Exons 5 to 7 were flanked by loxP sites.  
Colony maintenance Homozygote x Homozygote [or Crossing to C57BL/6JJmsSlc]  
Health Report
Gene Details
Promoter No Data  
 1 Symbol FRT  
Symbol name yeast FRT (flippase recombination target) site  
Chromosome 16  
Common name No Data  
Symbol description No Data  
 2 Symbol Nfkbiz  
Symbol name nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta  
Chromosome 16  
Common name No Data  
Symbol description No Data  
 3 Symbol loxP  
Symbol name phage P1 loxP  
Chromosome 16  
Common name No Data  
Symbol description No Data  
References   
Research applications Cre/loxP system,
FLP/frt system  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.  
Additional information
 1 No Data  
 2 Genotyping protocol <PCR>  
Depositor Maruyama, Takashi (Gifu University, Graduate School of Medicine)  Maruyama, Takashi 
Strain Status /
Availability
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