Strain Data Sheet
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Data update: May 23, 2017
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RBRC No. RBRC02189  
Type TransgeneCartagena  
Species Mus musculus  
Strain name C57BL/6Cr-Tg(Pcdh21-cre)BYoko  
Former Common name Pcdh21-nCre, C57BL/6  
H-2 Haplotype No Data  
Background strain C57BL/6  
Appearance
 1 Appearance black  
Genotype a/a B/B C/C  
Strain development Developed by Dr. Mineto Yokoi Kyoto University Guraduate School of Medicine nin 2004.  
Strain description This transgenic mice express the cre recombinase gene under the control of the Pcdh21 gene promoter. This can be used to make an conditional knock-out by crossing with the other genetically-engineered mice that have floxed genes. The expression of cre recombinase was observed in the mitral/tufted cells that are projection neurons in the olfactory bulb.  
Colony maintenance Backcross to C57BL/6 (Hemizygote x C57BL/6CrSlc)  
Health Report
Gene Details
Promoter Pcdh21 promoter  
 1 Symbol tTA  
Symbol name tetracycline-transactivator gene  
Chromosome UN  
Common name E. coli tet repressor (TetR), herpes simplex virus (HSV)VP16 activation domain  
Symbol description No Data  
 2 Symbol cre  
Symbol name Phage P1 Cre recombinase  
Chromosome UN  
Common name No Data  
Symbol description No Data  
References Genesis 2005 Sep;43(1):12-6.  
Transgenic expression of Cre recombinase in mitral/tufted cells of the olfactory bulb.
Research applications Cre/loxP system,
Neurobiology Research,
Tet system  
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Genesis, 43, 12-16 (2005).  
Additional information
 1 Genetic Background  
 2 Genotyping protocol <PCR>  
Depositor Yokoi, Mineto (Graduate School of Medicine, Kyoto University)  Yokoi, Mineto 
Strain Status /
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